Cbd Bath Bombs Reviewed: Soaking In Cbd
They mentioned several rat and mice studies that show CBD can affect neuroplastic changes such as the creation of new nerve cell and synaptic remodeling in the hippocampus of the brain. They also discussed some studies in rats that showed CBD as neuroprotective by preventing neurotoxicity and decreasing nerve cell damage. This 2018 study was a review of studies that talked about therapeutic uses of CBD, one of which was neuroplasticity increases. The authors concluded that the neuroprotective effects of CBD are due to decreased inflammation, rather than neuroplasticity changes. This is a different conclusion than the other studies and may be due to the fact that these rats had diabetes, while the others did not.
Specifically, they looked at the motor cortex of the brain, which is the part of the brain that affects movement. Since their study population was made up of MS patients, this makes sense because they have motor coordination problems as part of their disease. This 2009 study looked at the effects of Sativex, which contains both THC and CBD, on synaptic plasticity in humans with multiple sclerosis . The authors conclude that CBD can prevent stress by activating CB1 and CB2 receptors which recruit proteins in the brain involved with creating new nerve cells and remodeling dendrites. This 2018 study looked at repeated dosing of CBD at 30 mg/kg for 14 days in mice to see if it is facilitated by cannabinoid receptors and if it affects the creation of new nerve cells or remodeling of dendrites .
More importantly, it has been observed to play a part in neurogenesis and neuroplasticity, key functions of brain health and development. Thanks to this understanding, products, and strains can be engineered to contain specific cannabinoids. This way, a particular effect can be achieved, whether anti-inflammation, reduced stress, euphoria or energized creativity. Importantly, cannabinoids aren’t directly produced by cannabis. Cannabinoid acids are concentrated in cannabis resin, which need activation by decarboxylation .
Let’s take a closer look at cannabinoids — how they work, what their effects are and how many of them exist. It is always best practice to talk with a health care professional before using CBD to help with any health conditions you may have. They can help you evaluate the research and decide if it is the best option for you. They can also help you determine if any drug interactions exist with any current medications you might be taking and give suggestions for how to avoid them.
This 2005 study used a synthetic cannabinoid in rats to determine if cannabinoids can promote the creation of new nerve cells. The authors suggest that the mechanism behind this is the ability of cannabinoids, such as CBD, to bind to the CB1 receptor which promotes proliferation of nerve cells. They concluded that CBD may work by creating new nerve cells in the hippocampus of the brain, which led to anxiety relief in the mice.
How Cbd Oil Works To Help With Memory Loss
Smoking, vaping or cooking cannabis starts a reaction that produces cannabinoids form the secretions of cannabinoid acid. The fascinating part is that different cannabinoids produce different effects according to the type and location of receptor they interact with. Cannabinoids are naturally occurring chemical compounds that are found in cannabis, and often unique to the plant. They’re the reason you may feel a psychoactive high or therapeutic pain relief after consuming cannabis.
- Our data suggest that CBD acts on σ1R to alleviate the manifestation of epileptic syndrome, to protect against neural damage caused by vascular ischemia and to enhance the antinociception promoted by morphine.
- These findings suggest the implication of σ1R in other beneficial activities attributed to this phytocannabinoid.
- Moreover, σ1R ligands also exhibit antidepressant, anxiolytic, neuroprotective and antioxidative effects .
- Moreover, CBD exhibits anti-neuropathic effects and modulates morphine antinociception in mice .
Further exploration into the difference in neuroplasticity changes between those affected with diabetes and those that are not would be an interesting area of future research. They found that CBD did improve memory performance and reduced inflammation in the hippocampus region of the brain. Interestingly enough, they found that CBD did not affect neuroplasticity markers in these rats. This 2019 study looked at the effects of CBD neuroinflammation and neuroplasticity in rats with diabetes. They found that the endocannabinoid system does play a role in synaptic plasticity.
In this study they looked at brain proteins involved with these processes when giving rats CBD. They found that CBD helped restore the damage from the iron by CBD oil bringing the protein levels back to the normal levels they saw in the control group. Of note, this study only discussed cannabinoids as a whole and did not mention CBD specifically.